Country of Issue: United States
Patent Number: 8,840,919
Issue Date: September 23, 2014
Domain: Manufacturing of oral films
A medicant composition is provided. The composition includes a film layer and a powder matrix layer. The powder matrix layer includes a medicant. The powder matrix layer is applied to the film layer by admixing particulate to form a powder matrix and by then applying the powder matrix to the film layer by any desired method. The composition of the powder matrix is varied to alter the dissolution rate of the medicant, the adhesion of the medicant composition, and other physical properties of the powder matrix. The powder matrix layer can be cured.
Patent Number: 9,155,698
Issue Date: October 13, 2015
Issue Date: September 3, 2019
Domain: Compositions for oral films
Country: United States
Patent Number: 8,999,372
Issue Date: April 7, 2015
Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use are disclosed.
Patent Number: 9,044,390
Issue Date: June 2, 2015
Domain: Isolation of Cannabis extracts
The present invention provides for methods of obtaining an extract of Cannabis plant material as well as subsequent processing of the extract to provide a concentrate of Cannabis. The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of Cannabis, as well as methods of medical treatment that include administering the pharmaceutical dosage forms.
Patent Number: 9,186,386
Issue Date: November 11, 2015
Patent Number: 9,980,996
Issue Date: May 29, 2018
Patent Number: 10,092,611
Issue Date: October 9, 2018
Domain: Oral films containing Cannabis concentrate
Patent Number: 10,238,705
Issue Date: March 26, 2019
Patent Number: 10,413,516
Issue Date: September 17, 2019
Domain: Manufacturing of high load oral films
A method of preparing a thin film, the method comprising: (a) mixing a lipid, emulsifier, and solvent to provide a uniform first mixture; (b) contacting an active ingredient with the uniform first mixture to provide a thickened second mixture; (c) contacting a binder with the thickened second mixture to provide a slurry; and (d) hot extruding, casting, and condensing the slurry to provide the thin film; or cooling, shearing, mixing, casting, and condensing the slurry to provide the thin film.