The longstanding, successful use of herbal drug combinations in traditional medicine makes it necessary to find a rationale for the pharmacological and therapeutic superiority of many of them in comparison to isolated single constituents. This review describes many examples of how modern molecular–biological methods (including new genomic technologies) can enable us to understand the various synergistic mechanisms underlying these effects.

Wagner, Hildebert. (2010). Synergy research: Approaching a new generation of phytopharmaceuticals. Fitoterapia. 82. 34-7. 10.1016/j.fitote.2010.11.016.